RNU6-14P

Across TCGA pan-cancer cohorts, RNU6-14P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNU6-14P data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RNU6-14P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-14P expression acts as an unfavorable survival marker.

MESO, UCEC, and ACC are the cancer types where RNU6-14P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	II,III,IV	0.071	0.572	<.001	72	view →
UCEC	DFS	Tertile	All	0.766	0.903	.001	66	view →
ACC	DFS	Tertile	IV	0.010	0.383	<.001	45	view →
HNSC	DFS	Tertile	III,IV	0.354	0.667	.007	36	view →
LUSC	OS	Tertile	III,IV	0.054	0.768	<.001	27	view →
SKCM	OS	Tertile	III,IV	0.142	0.808	<.001	18	view →
LUAD	DFS	Tertile	IV	0.357	0.710	.019	18	view →
GBM	OS	Tertile	All	0.129	0.417	.001	18	view →
THYM	DFS	Tertile	III,IV	0.214	1.000	.008	18	view →
KIRC	OS	Tertile	All	0.719	0.816	.045	6	view →
PRAD	DFS	Tertile	All	0.797	0.938	.027	6	view →
THCA	DFS	Tertile	All	0.806	0.920	.038	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

RNU6-14P–MESO (OS)

Open the MESO breakdown →