RNU6-148P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-148P RNA is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated RNU6-148P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU6-148P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-148P expression acts as an unfavorable survival marker, although some lineages such as LAML show a favorable association.

BLCA, UCEC, and STAD are the cancer types where RNU6-148P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCAOSTertileAll0.0510.720<.001144view →
UCECDFSTertileAll0.2400.842<.00190view →
STADOSTertileII,III,IV0.1590.566.01272view →
LAMLDFSTertileAll0.8590.318.01018view →
UVMOSTertileAll0.3150.711.0499view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RNU6-148P–BLCA (OS)

Kaplan–Meier survival curve for RNU6-148P RNA-high vs -low samples in BLCA.

Open the BLCA breakdown →

Exploration