RNU6-143P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-143P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNU6-143P data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher RNU6-143P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-143P expression acts as an unfavorable survival marker, although some lineages such as ESCA and BRCA show a favorable association.

PAAD, LIHC, and UCS are the cancer types where RNU6-143P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PAADDFSTertileAll0.0980.505.00372view →
LIHCDFSTertileAll0.0880.557<.00142view →
UCSDFSTertileIII,IV0.1200.441.00436view →
THYMOSTertileAll0.1860.930.00324view →
KIRPDFSTertileIII,IV0.0400.691<.00118view →
ESCAOSTertileIII,IV0.8770.364.01218view →
SARCDFSTertileAll0.2470.605.01318view →
BLCAOSTertileIV0.1950.484.0399view →
CHOLDFSTertileAll0.1180.495.0449view →
SKCMDFSTertileAll0.4350.775<.0019view →
BRCADFSTertileIII,IV1.0000.458.0426view →
KIRCDFSTertileAll0.3310.653.0256view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

RNU6-143P–PAAD (DFS)

Kaplan–Meier survival curve for RNU6-143P RNA-high vs -low samples in PAAD.

Open the PAAD breakdown →

Exploration