Across TCGA pan-cancer cohorts, RNU6-13P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU6-13P’s most consistent transcriptional readouts.

The strongest signal is observed in rectum adenocarcinoma (READ), where RNU6-13P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-13P is over-expressed in tumor, although a few such as READ and LUSC show the opposite, repressed pattern.

READ, HNSC, and LUSC are the cancer types where RNU6-13P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-13P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
READ	Female	All	−0.374	.043	1	view →
HNSC	All	III,IV	+0.103	.044	1	view →
LUSC	Male	All	−0.086	.021	1	view →
KIRC	Male	All	−0.040	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNU6-13P RNA expression & survival · all RNU6-13P data types