RNU6-136P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-136P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-136P data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RNU6-136P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-136P expression acts as an unfavorable survival marker, although some lineages such as HNSC and READ show a favorable association.

ACC, TGCT, and UVM are the cancer types where RNU6-136P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCOSTertileAll0.2070.676<.00190view →
TGCTOSTertileIII,IV0.0031.000<.00154view →
UVMOSTertileAll0.2180.696.01436view →
UCECDFSTertileAll0.8350.906.00424view →
KIRPDFSTertileAll0.8090.938.00315view →
HNSCDFSTertileAll0.7960.681.02115view →
SKCMOSTertileIV0.4150.861.0149view →
READDFSTertileII,III,IV1.0000.773.0376view →
KIRCDFSMedianIV0.6140.348.0244view →
LGGOSTertileAll0.6960.816.0383view →
ESCAOSMedianII,III,IV0.6171.000.0493view →
DLBCOSTertileAll0.7380.951.0493view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

Exploration