RNU6-1322P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1322P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU6-1322P data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RNU6-1322P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1322P expression acts as an unfavorable survival marker, although some lineages such as LAML and SKCM show a favorable association.

ACC, UVM, and LAML are the cancer types where RNU6-1322P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCOSTertileAll0.2100.847<.00196view →
UVMOSTertileII,III,IV0.2180.718.00672view →
LAMLDFSMedianAll0.6560.230<.00134view →
DLBCOSTertileIII,IV0.1750.874.02527view →
LGGDFSTertileAll0.6730.840.00515view →
SKCMOSTertileIII,IV0.9590.798.02812view →
BRCADFSTertileIII,IV0.7390.887.01912view →
HNSCDFSTertileIV0.3480.594.02012view →
KIRPDFSTertileIII,IV1.0000.305.0329view →
GBMDFSTertileAll0.4950.243.0499view →
PCPGOSTertileAll0.6700.944.0419view →
BLCAOSTertileII,III,IV0.7710.588.0316view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

Exploration