RNU6-1318P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1318P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU6-1318P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RNU6-1318P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1318P expression acts as an unfavorable survival marker, although some lineages such as BRCA and LAML show a favorable association.

UVM, ESCA, and ACC are the cancer types where RNU6-1318P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UVMOSTertileAll0.0370.858<.001108view →
ESCADFSMedianIV0.2050.634.00624view →
ACCDFSTertileII,III,IV0.2260.725.00918view →
UCECOSTertileIV0.2770.605.01318view →
BRCAOSTertileIII,IV0.7790.480.03212view →
THYMOSTertileII,III,IV0.5570.983<.00112view →
LAMLDFSTertileAll0.6840.427.03410view →
LIHCOSTertileII,III,IV0.1240.623.0119view →
HNSCOSTertileIV0.6240.320.0196view →
READOSTertileAll1.0000.598.0426view →
Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

Exploration