RNU6-1315P

Across TCGA pan-cancer cohorts, RNU6-1315P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNU6-1315P’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RNU6-1315P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-1315P is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, KICH, and BLCA are the cancer types where RNU6-1315P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-1315P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.273	<.001	6	view →
KICH	All	All	−0.215	.005	4	view →
BLCA	All	All	+0.238	.024	2	view →
KIRC	Male	IV	+0.222	.013	2	view →
LUAD	Female	All	−0.175	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

RNU6-1315P–THCA

Open the THCA breakdown →