RNU6-1298P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1298P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU6-1298P data layer.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher RNU6-1298P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1298P expression acts as an unfavorable survival marker, although some lineages such as KIRC show a favorable association.

GBM, SKCM, and LUSC are the cancer types where RNU6-1298P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
GBMDFSTertileAll0.0520.258<.00136view →
SKCMDFSTertileII,III,IV0.0400.683<.00127view →
LUSCOSTertileAll0.1730.724.01227view →
UCECOSTertileAll0.4000.681.02724view →
KIRPDFSTertileAll0.6590.920.00821view →
LIHCOSTertileAll0.2310.690.01818view →
TGCTOSTertileAll0.7710.968.00418view →
STADDFSTertileIV0.0830.379.0019view →
KIRCDFSTertileAll0.9300.796.0466view →
Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

Exploration