RNU6-1294P

Across TCGA pan-cancer cohorts, RNU6-1294P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNU6-1294P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RNU6-1294P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNU6-1294P expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

HNSC, LIHC, and THCA are the cancer types where RNU6-1294P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	II,III,IV	0.876	0.674	.005	111	view →
LIHC	OS	Tertile	III,IV	0.110	0.625	<.001	81	view →
THCA	OS	Tertile	II,III,IV	0.857	0.990	<.001	57	view →
UCEC	DFS	Tertile	III,IV	0.580	0.808	.003	48	view →
MESO	DFS	Tertile	II,III,IV	0.096	0.547	<.001	45	view →
OV	OS	Tertile	IV	0.383	0.727	<.001	36	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	36	view →
STAD	DFS	Tertile	IV	0.095	0.458	<.001	15	view →
SKCM	DFS	Tertile	II,III,IV	0.213	0.593	.037	9	view →
PCPG	DFS	Tertile	All	0.438	0.860	.045	9	view →
READ	DFS	Tertile	III,IV	0.082	0.760	.001	9	view →
THYM	DFS	Tertile	II,III,IV	0.701	0.961	.008	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

RNU6-1294P–HNSC (DFS)

Open the HNSC breakdown →