RNU6-128P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-128P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU6-128P data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher RNU6-128P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-128P expression acts as an unfavorable survival marker.

SKCM, ACC, and UVM are the cancer types where RNU6-128P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SKCMOSTertileIII,IV0.3350.713<.00175view →
ACCOSTertileIII,IV0.1450.766<.00163view →
UVMOSTertileAll0.2200.917<.00154view →
KIRCDFSTertileIV0.0920.620.00236view →
ESCAOSTertileII,III,IV0.1030.868<.00129view →
THYMOSTertileAll0.3810.879.00318view →
GBMDFSTertileAll0.0860.300<.0019view →
LUADDFSTertileIII,IV0.2060.670.0159view →
STADDFSTertileIV0.1020.412.0199view →
Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

Exploration