RNU6-1281P

Across TCGA pan-cancer cohorts, RNU6-1281P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU6-1281P data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher RNU6-1281P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1281P expression acts as an unfavorable survival marker, although some lineages such as STAD show a favorable association.

CHOL, UCEC, and READ are the cancer types where RNU6-1281P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CHOL	OS	Tertile	All	0.024	0.728	<.001	108	view →
UCEC	DFS	Tertile	All	0.756	0.898	.031	48	view →
READ	DFS	Tertile	III,IV	0.437	0.765	.006	45	view →
LUSC	OS	Tertile	III,IV	0.086	0.664	<.001	18	view →
HNSC	OS	Tertile	IV	0.029	0.643	<.001	18	view →
TGCT	OS	Tertile	All	0.694	0.968	.009	18	view →
PRAD	OS	Tertile	All	0.958	0.995	.001	18	view →
ESCA	OS	Quartile	All	0.636	1.000	.049	3	view →
STAD	OS	Quartile	II,III,IV	0.614	0.342	.041	2	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

RNU6-1281P–CHOL (OS)

Open the CHOL breakdown →