Across TCGA pan-cancer cohorts, RNU6-1275P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RNU6-1275P’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RNU6-1275P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-1275P is over-expressed in tumor, although a few such as BRCA and STAD show the opposite, repressed pattern.

BRCA, STAD, and HNSC are the cancer types where RNU6-1275P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-1275P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	−0.195	.047	2	view →
STAD	All	All	−0.159	.040	1	view →
HNSC	Male	All	−0.072	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: RNU6-1275P RNA expression & survival · all RNU6-1275P data types