RNU6-1272P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1272P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-1272P data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher RNU6-1272P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1272P expression acts as an unfavorable survival marker, although some lineages such as LAML and OV show a favorable association.

TGCT, DLBC, and LAML are the cancer types where RNU6-1272P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
TGCTDFSTertileIII,IV0.0101.000<.00172view →
DLBCDFSTertileII,III,IV0.0650.829<.00154view →
LAMLDFSTertileAll0.5940.187<.00152view →
CESCOSTertileIV0.1210.591.02936view →
ESCAOSTertileAll0.4071.000.00318view →
THCADFSTertileII,III,IV0.6780.854.01018view →
LIHCDFSTertileAll0.1600.445.00118view →
COADDFSTertileII,III,IV0.2130.490.01715view →
SKCMOSTertileIV0.1790.727<.00115view →
OVDFSTertileIV0.5150.225.03712view →
KICHDFSTertileAll0.2940.888.00212view →
GBMOSTertileAll0.2490.438.0029view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

Exploration