RNU6-1270P

Across TCGA pan-cancer cohorts, RNU6-1270P RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated RNU6-1270P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RNU6-1270P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1270P expression acts as an unfavorable survival marker, although some lineages such as LAML show a favorable association.

HNSC, LAML, and BLCA are the cancer types where RNU6-1270P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	II,III,IV	0.122	0.697	<.001	54	view →
LAML	DFS	Tertile	All	0.771	0.525	.010	24	view →
BLCA	DFS	Tertile	All	0.245	0.627	.048	18	view →
KIRC	DFS	Tertile	IV	0.127	0.630	.039	18	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RNU6-1270P–HNSC (DFS)

Open the HNSC breakdown →