RNU6-126P

Across TCGA pan-cancer cohorts, RNU6-126P RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated RNU6-126P data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RNU6-126P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNU6-126P expression acts as an unfavorable survival marker, although some lineages such as BRCA and HNSC show a favorable association.

BRCA, KIRP, and HNSC are the cancer types where RNU6-126P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Median	All	0.968	0.929	<.001	50	view →
KIRP	OS	Tertile	II,III,IV	0.487	0.883	.014	44	view →
HNSC	DFS	Tertile	III,IV	0.803	0.642	.006	41	view →
UCS	DFS	Quartile	II,III,IV	0.608	0.188	.010	36	view →
OV	DFS	Tertile	II,III,IV	0.591	0.496	.012	30	view →
UVM	OS	Quartile	III,IV	0.269	0.703	.001	24	view →
STAD	DFS	Quartile	IV	0.096	0.696	.001	18	view →
UCEC	DFS	Median	II,III,IV	0.778	0.849	.024	16	view →
MESO	DFS	Median	IV	0.185	0.440	.010	15	view →
PAAD	OS	Median	III,IV	0.629	1.000	.022	14	view →
CHOL	OS	Tertile	III,IV	0.376	1.000	.024	12	view →
PCPG	OS	Tertile	All	0.944	1.000	.045	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

RNU6-126P–BRCA (DFS)

Open the BRCA breakdown →