RNU6-1265P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1265P RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated RNU6-1265P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RNU6-1265P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1265P expression acts as an unfavorable survival marker.

UVM, KIRC, and GBM are the cancer types where RNU6-1265P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UVMOSTertileAll0.0370.858<.001108view →
KIRCDFSTertileIII,IV0.1270.744.00272view →
GBMOSTertileAll0.1040.415.02418view →
BLCAOSTertileAll0.4800.725.03712view →
COADOSTertileIII,IV0.1830.696.0499view →
BRCADFSTertileII,III,IV0.1720.522.0076view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RNU6-1265P–UVM (OS)

Kaplan–Meier survival curve for RNU6-1265P RNA-high vs -low samples in UVM.

Open the UVM breakdown →

Exploration