RNU6-1263P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1263P RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated RNU6-1263P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-1263P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1263P expression acts as an unfavorable survival marker, although some lineages such as UCS and SKCM show a favorable association.

KIRC, UCEC, and ACC are the cancer types where RNU6-1263P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSTertileAll0.7190.848<.001114view →
UCECDFSTertileIV0.2630.720.01742view →
ACCDFSTertileAll0.2470.611.02536view →
KIRPDFSTertileAll0.7650.927<.00135view →
UCSOSMedianII,III,IV0.8130.469.01130view →
SKCMOSQuartileII,III,IV0.9250.813.00329view →
COADDFSTertileAll0.2490.537.00227view →
READDFSTertileIII,IV0.4310.766.01624view →
CESCOSTertileIII,IV0.9230.580.02618view →
MESOOSTertileIV0.0360.602<.00118view →
LUSCDFSTertileIII,IV0.3390.790.00818view →
ESCADFSTertileAll1.0000.538.01415view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

Exploration