RNU6-1256P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1256P RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated RNU6-1256P data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher RNU6-1256P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNU6-1256P expression acts as an unfavorable survival marker, although some lineages such as OV and STAD show a favorable association.

OV, SKCM, and CHOL are the cancer types where RNU6-1256P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
OVDFSTertileII,III,IV0.6170.517.00854view →
SKCMOSTertileIV0.1790.727<.00136view →
CHOLOSTertileAll0.0190.800<.00136view →
STADOSTertileIII,IV0.6400.285.00734view →
UCECOSTertileAll0.5590.689.00730view →
PAADOSTertileAll0.2740.620.00427view →
THYMDFSTertileII,III,IV0.1450.873<.00118view →
UCSDFSTertileAll0.1840.528.03518view →
UVMOSTertileAll0.2920.674.03518view →
LAMLDFSTertileAll0.5130.299.01718view →
KIRPDFSTertileIII,IV0.1650.614.00518view →
HNSCOSTertileIV0.8420.382.02412view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

RNU6-1256P–OV (DFS)

Kaplan–Meier survival curve for RNU6-1256P RNA-high vs -low samples in OV.

Open the OV breakdown →

Exploration