RNU6-1248P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1248P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU6-1248P data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher RNU6-1248P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1248P expression acts as an unfavorable survival marker, although some lineages such as OV and ESCA show a favorable association.

UCS, HNSC, and KIRC are the cancer types where RNU6-1248P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCSOSTertileII,III,IV0.0010.616<.00172view →
HNSCDFSTertileII,III,IV0.2540.601.00172view →
KIRCDFSTertileIII,IV0.4460.771.00142view →
OVOSTertileII,III,IV0.9050.820.01336view →
SARCOSTertileAll0.1730.525.00733view →
ESCAOSQuartileII,III,IV0.6620.400.02230view →
SKCMDFSTertileIII,IV0.4740.222.00827view →
BLCAOSTertileIV0.3260.611.00321view →
THCADFSTertileAll0.8050.928.01418view →
READDFSTertileII,III,IV0.1670.526.0409view →
Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

Exploration