RNU6-1245P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1245P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-1245P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-1245P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1245P expression acts as an unfavorable survival marker, although some lineages such as MESO show a favorable association.

KIRC, MESO, and HNSC are the cancer types where RNU6-1245P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSTertileIV0.2450.526.00572view →
MESODFSTertileIII,IV1.0000.256.01136view →
HNSCDFSTertileII,III,IV0.2120.561.01436view →
THCAOSTertileIV0.7511.000.01427view →
SARCOSTertileAll0.1810.521.01224view →
UCSOSTertileIV0.2690.624.04218view →
TGCTOSTertileAll0.8670.990.00918view →
LUADOSTertileIV0.3250.724.02918view →
UCECDFSTertileIV0.2060.704.03318view →
LIHCOSTertileII,III,IV0.3480.625.02418view →
SKCMDFSTertileIV0.0160.541.0089view →
ESCADFSTertileII,III,IV0.1310.776.0439view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

Exploration