RNU6-1238P

Across TCGA pan-cancer cohorts, RNU6-1238P RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated RNU6-1238P data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher RNU6-1238P RNA is associated with better overall survival. In most high-consensus cancer types, elevated RNU6-1238P expression acts as an unfavorable survival marker, although some lineages such as SKCM and UCS show a favorable association.

SKCM, LIHC, and KICH are the cancer types where RNU6-1238P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Tertile	II,III,IV	0.523	0.311	<.001	86	view →
LIHC	DFS	Tertile	All	0.418	0.602	<.001	66	view →
KICH	OS	Median	III,IV	0.357	0.907	.006	36	view →
UCS	OS	Quartile	II,III,IV	0.863	0.340	.004	36	view →
UVM	DFS	Median	All	0.322	0.701	<.001	35	view →
KIRC	DFS	Median	IV	0.231	0.441	.005	28	view →
LGG	DFS	Tertile	All	0.780	0.889	<.001	25	view →
ACC	OS	Median	All	0.879	0.437	.009	21	view →
CHOL	DFS	Median	All	0.576	0.245	.023	15	view →
CESC	OS	Median	II,III,IV	0.896	0.753	.021	10	view →
COAD	OS	Tertile	IV	0.748	0.396	.016	7	view →
DLBC	DFS	Median	III,IV	0.383	0.984	.043	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

RNU6-1238P–SKCM (OS)

Open the SKCM breakdown →