RNU6-1225P

Across TCGA pan-cancer cohorts, RNU6-1225P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RNU6-1225P data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RNU6-1225P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1225P expression acts as an unfavorable survival marker, although some lineages such as BLCA show a favorable association.

LUSC, PAAD, and KIRC are the cancer types where RNU6-1225P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	II,III,IV	0.289	0.737	.001	87	view →
PAAD	OS	Tertile	II,III,IV	0.232	0.561	<.001	36	view →
KIRC	DFS	Tertile	IV	0.173	0.624	.005	36	view →
KIRP	OS	Tertile	II,III,IV	0.180	0.771	.007	27	view →
COAD	OS	Tertile	II,III,IV	0.320	0.796	.006	18	view →
BLCA	DFS	Tertile	IV	1.000	0.307	.031	15	view →
ESCA	DFS	Median	II,III,IV	0.418	0.889	.042	15	view →
SARC	OS	Tertile	All	0.618	0.865	.045	3	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RNU6-1225P–LUSC (OS)

Open the LUSC breakdown →