RNU6-1222P

Across TCGA patient cohorts, RNU6-1222P RNA expression is significantly associated with the go_rna of many other GO terms, with 5,223 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-1222P-associated GO terms across cancer lineages are Macromolecule methylation, Lung morphogenesis, and Positive regulation of small molecule metabolic process. Each is linked with RNU6-1222P in more than 6 cancer types. Because this analysis shows association rather than direction, both RNU6-1222P-to-partner and partner-to-RNU6-1222P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macromolecule methylation grouped by RNU6-1222P-low versus RNU6-1222P-high in BRCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-1222P→partner) and Y-score (partner→RNU6-1222P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	Macromolecule methylation →	+0.044	+0.063	<.001	<.001	3	7
BRCA	Lung morphogenesis →	+0.060	+0.038	<.001	.002	3	6
STAD	Positive regulation of small molecule metabolic process →	+0.031	+0.340	<.001	<.001	3	6
COAD	Regulation of stem cell differentiation →	+0.089	+0.105	<.001	.004	2	7
BRCA	Endocytic recycling →	+0.051	+0.053	<.001	.006	2	7
BRCA	Regulation of mRNA splicing, via spliceosome →	+0.088	+0.068	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,223 associations by consensus.

Macromolecule methylation by RNU6-1222P expression — BRCA

Explore this box plot interactively →