RNU6-1218P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1218P RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated RNU6-1218P data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher RNU6-1218P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1218P expression acts as an unfavorable survival marker.

ESCA, BLCA, and THCA are the cancer types where RNU6-1218P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ESCAOSTertileII,III,IV0.3950.710.00163view →
BLCADFSTertileAll0.1590.625.01645view →
THCAOSTertileAll0.5940.942<.00136view →
BRCAOSTertileII,III,IV0.6680.913.01918view →
SKCMDFSTertileAll0.0230.738<.00118view →
UCECOSTertileII,III,IV0.4670.770.03618view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RNU6-1218P–ESCA (OS)

Kaplan–Meier survival curve for RNU6-1218P RNA-high vs -low samples in ESCA.

Open the ESCA breakdown →

Exploration