RNU6-1215P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1215P RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated RNU6-1215P data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher RNU6-1215P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1215P expression acts as an unfavorable survival marker, although some lineages such as ESCA and CESC show a favorable association.

READ, COAD, and UCEC are the cancer types where RNU6-1215P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
READDFSTertileAll0.5470.878.00175view →
COADOSTertileII,III,IV0.3480.630.00260view →
UCECDFSTertileAll0.8340.912.00160view →
ESCAOSTertileIII,IV0.5360.277.00839view →
UVMOSTertileAll0.2480.769.00736view →
CESCDFSMedianAll0.8720.785.01220view →
LIHCDFSTertileAll0.3940.565.00318view →
LUSCOSTertileII,III,IV0.8070.709.01815view →
BRCAOSQuartileAll0.6770.563.01913view →
STADDFSQuartileIV0.0930.469.02712view →
KIRPOSTertileAll0.8850.946.01312view →
LUADOSMedianIII,IV0.5580.743.0254view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

Exploration