RNU6-118P

Across TCGA pan-cancer cohorts, RNU6-118P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNU6-118P’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RNU6-118P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-118P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

THCA, HNSC, and LIHC are the cancer types where RNU6-118P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-118P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	All	−0.666	.003	4	view →
HNSC	All	All	+0.408	<.001	4	view →
LIHC	All	All	+0.285	.012	4	view →
CHOL	All	All	+1.212	<.001	3	view →
PRAD	All	All	+0.456	.006	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

RNU6-118P–THCA

Open the THCA breakdown →