RNU6-1188P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1188P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNU6-1188P data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher RNU6-1188P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1188P expression acts as an unfavorable survival marker, although some lineages such as COAD and LAML show a favorable association.

LIHC, TGCT, and UCS are the cancer types where RNU6-1188P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LIHCDFSTertileAll0.0420.546<.00172view →
TGCTOSTertileIII,IV0.0031.000<.00172view →
UCSOSTertileIII,IV0.1020.591<.00172view →
SKCMOSTertileAll0.3950.793<.00154view →
DLBCOSTertileAll0.0540.842<.00136view →
THCAOSTertileIV0.5791.000<.00130view →
THYMDFSTertileII,III,IV0.6080.907.00527view →
COADDFSTertileAll1.0000.676.01324view →
LAMLDFSMedianAll0.4740.282.00618view →
PRADOSTertileAll0.9720.996.00618view →
CESCDFSTertileAll0.9610.805.02012view →
LGGDFSTertileAll0.7490.839.0393view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

Exploration