RNU6-1186P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1186P RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated RNU6-1186P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-1186P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1186P expression acts as an unfavorable survival marker.

KIRC, BLCA, and SKCM are the cancer types where RNU6-1186P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSTertileIII,IV0.1410.489<.001162view →
BLCADFSTertileAll0.1790.630<.001126view →
SKCMOSTertileAll0.2320.787.00281view →
KIRPOSTertileII,III,IV0.1610.771.00251view →
LIHCOSTertileAll0.1180.783<.00136view →
SARCOSTertileAll0.1080.827<.00127view →
LGGDFSTertileAll0.4040.834.0166view →
Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

Exploration