RNU6-1180P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1180P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU6-1180P data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RNU6-1180P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1180P expression acts as an unfavorable survival marker, although some lineages such as BLCA and LAML show a favorable association.

KICH, KIRC, and HNSC are the cancer types where RNU6-1180P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KICHDFSTertileAll0.0430.971<.00199view →
KIRCDFSTertileAll0.3990.807<.00196view →
HNSCOSTertileAll0.2650.713.00954view →
BLCADFSTertileIII,IV0.5060.282<.00148view →
SKCMOSTertileIII,IV0.2160.721.00145view →
UCECDFSTertileIV0.2060.704.03318view →
LAMLDFSTertileAll0.7460.345.03812view →
CESCOSTertileAll0.1840.593.02712view →
COADDFSTertileII,III,IV0.5030.743.0396view →
Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

Exploration