RNU6-117P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-117P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RNU6-117P data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher RNU6-117P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-117P expression acts as an unfavorable survival marker, although some lineages such as PAAD show a favorable association.

STAD, BRCA, and OV are the cancer types where RNU6-117P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADDFSQuartileAll0.4100.592<.001144view →
BRCADFSTertileIII,IV0.5320.807.00266view →
OVDFSTertileIV0.2110.483.01036view →
LUSCOSTertileII,III,IV0.2990.635.01921view →
THYMDFSTertileAll0.1340.871<.00118view →
THCADFSTertileIV0.2700.832.01418view →
UCECOSTertileAll0.8600.928.01918view →
SARCDFSTertileAll0.0790.611<.00118view →
LGGOSTertileAll0.5110.830.0429view →
PCPGDFSTertileAll0.3210.834.0466view →
PAADOSMedianII,III,IV0.5890.391.0452view →
Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

Exploration