RNU6-1161P

Across TCGA pan-cancer cohorts, RNU6-1161P RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated RNU6-1161P data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RNU6-1161P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNU6-1161P expression acts as an unfavorable survival marker, although some lineages such as BRCA and BLCA show a favorable association.

BRCA, SKCM, and BLCA are the cancer types where RNU6-1161P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Tertile	All	0.977	0.939	.004	72	view →
SKCM	OS	Tertile	IV	0.297	0.777	<.001	57	view →
BLCA	DFS	Tertile	II,III,IV	0.687	0.530	.002	53	view →
LIHC	OS	Tertile	II,III,IV	0.569	0.778	.001	48	view →
LAML	DFS	Tertile	All	0.154	0.575	.038	36	view →
READ	DFS	Median	All	0.728	0.899	.001	36	view →
PAAD	OS	Tertile	All	0.251	0.534	.004	33	view →
SARC	DFS	Tertile	All	0.097	0.604	<.001	27	view →
ACC	OS	Tertile	All	0.118	0.624	.038	18	view →
ESCA	DFS	Tertile	IV	0.252	0.704	.024	12	view →
COAD	DFS	Tertile	II,III,IV	0.688	0.826	.012	10	view →
CHOL	OS	Median	II,III,IV	0.300	0.775	.011	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

RNU6-1161P–BRCA (DFS)

Open the BRCA breakdown →