RNU6-1158P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1158P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNU6-1158P’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RNU6-1158P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-1158P is over-expressed in tumor, although a few such as COAD and LUAD show the opposite, repressed pattern.

COAD and LUAD are the cancer types where RNU6-1158P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-1158P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
COADAllIII,IV−0.183.0311view →
LUADAllII,III,IV−0.128.0451view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration