RNU6-1154P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1154P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNU6-1154P data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher RNU6-1154P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1154P expression acts as an unfavorable survival marker, although some lineages such as STAD and BLCA show a favorable association.

THCA, STAD, and LIHC are the cancer types where RNU6-1154P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
THCAOSTertileIV0.5791.000<.00160view →
STADOSTertileIV0.8760.172.00254view →
LIHCDFSTertileII,III,IV0.1550.487.00448view →
BLCAOSTertileIII,IV0.8960.398.00836view →
PAADOSTertileAll0.8300.434.02421view →
CHOLOSTertileAll0.1540.793.00418view →
UVMOSTertileAll0.2920.674.03518view →
ESCAOSTertileIII,IV0.6470.327.00514view →
KIRCDFSTertileIII,IV0.2890.510.02212view →
ACCOSTertileAll0.6180.917.0156view →
BRCADFSTertileIII,IV0.8300.438.0166view →
SKCMDFSTertileAll0.3310.181.0313view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

Exploration