RNA, U6 small nuclear 1153, pseudogeneGenealiases: []
Q-omics provides the consensus-scored RNU6-1153P profile across patient tissues and cancer cell-line models. RNU6-1153P expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in LUAD. Among the 18 cancer types available for tumor–normal comparison, RNU6-1153P is differentially expressed in 2, with the highest sampling consensus in KICH. Additionally, RNU6-1153P RNA expression shows 6,229 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight LUAD, KICH, and STAD as cancer lineages where RNU6-1153P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU6-1153P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU6-1153P survival associations across molecular data types. RNU6-1153P RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU6-1153P RNA expression–survival associations across cancer types. High RNU6-1153P expression shows unfavorable associations in READ, MESO, BLCA and PAAD, but favorable associations in LUAD and CESC. The LUAD Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .001). Together, the overview and detailed table identify LUAD as the clearest survival context for RNU6-1153P RNA expression.
This table summarizes RNU6-1153P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for RNU6-1153P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU6-1153P shows lower tumor expression in KICH and higher tumor expression in STAD. The KICH box plot shows higher RNU6-1153P RNA expression in normal versus tumor tissue (log2 FC = −0.448, t-test p = .003).
This table shows molecular features associated with RNU6-1153P in patient tissues and cancer cell lines. In patient samples, RNU6-1153P shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
