RNU6-1147P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1147P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-1147P data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher RNU6-1147P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1147P expression acts as an unfavorable survival marker, although some lineages such as LAML and BRCA show a favorable association.

CESC, TGCT, and DLBC are the cancer types where RNU6-1147P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CESCOSTertileIII,IV0.3420.777<.00196view →
TGCTOSTertileII,III,IV0.5010.996<.00172view →
DLBCOSTertileII,III,IV0.1720.949<.00142view →
KIRPDFSTertileIII,IV0.1250.613.01936view →
ESCADFSMedianII,III,IV0.4330.599.01627view →
UVMOSTertileAll0.2840.710.00924view →
THCADFSTertileII,III,IV0.8070.919.02024view →
OVDFSTertileIV0.3160.496.02518view →
THYMOSTertileIV0.2941.000.02518view →
LUADDFSTertileIV0.0470.565<.00118view →
READDFSTertileIV0.0820.619.00118view →
LAMLDFSMedianAll0.7030.445.00416view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

Exploration