RNU6-1146P

Across TCGA pan-cancer cohorts, RNU6-1146P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU6-1146P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RNU6-1146P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1146P expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

HNSC, UVM, and THCA are the cancer types where RNU6-1146P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.430	0.702	<.001	117	view →
UVM	DFS	Tertile	All	0.353	0.773	.001	105	view →
THCA	OS	Tertile	All	0.827	0.976	<.001	90	view →
MESO	DFS	Tertile	III,IV	0.195	0.390	.025	36	view →
ESCA	OS	Tertile	IV	0.095	0.512	.008	36	view →
ACC	OS	Tertile	All	0.188	0.820	<.001	36	view →
LAML	DFS	Tertile	All	0.209	0.588	.042	18	view →
LUSC	OS	Tertile	II,III,IV	0.100	0.780	<.001	18	view →
SKCM	DFS	Tertile	All	0.443	0.195	.033	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

RNU6-1146P–HNSC (DFS)

Open the HNSC breakdown →