RNU6-1145P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1145P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNU6-1145P data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RNU6-1145P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1145P expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

ACC, BRCA, and BLCA are the cancer types where RNU6-1145P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCOSTertileAll0.2390.810<.001153view →
BRCAOSTertileAll0.7120.928<.001138view →
BLCAOSTertileAll0.1160.693<.00190view →
SKCMOSTertileAll0.6010.877<.00187view →
KIRCDFSTertileIV0.3190.650.00272view →
READOSTertileII,III,IV0.0540.934<.00172view →
LUSCOSTertileIII,IV0.1260.664.00836view →
THYMDFSTertileII,III,IV0.1640.743.00127view →
LUADOSTertileAll0.0350.788<.00118view →
HNSCOSTertileIV0.6050.382.02818view →
LIHCOSTertileAll0.1700.563.01215view →
STADDFSTertileII,III,IV0.4730.714.0239view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

Exploration