RNU6-1143P

Across TCGA pan-cancer cohorts, RNU6-1143P RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated RNU6-1143P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RNU6-1143P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1143P expression acts as an unfavorable survival marker, although some lineages such as LAML and MESO show a favorable association.

UVM, ACC, and THCA are the cancer types where RNU6-1143P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.104	0.834	<.001	63	view →
ACC	DFS	Tertile	IV	0.010	0.383	<.001	51	view →
THCA	OS	Tertile	III,IV	0.605	0.907	.003	42	view →
LAML	DFS	Median	All	0.474	0.274	.001	36	view →
PAAD	OS	Tertile	All	0.361	0.631	<.001	27	view →
HNSC	OS	Tertile	IV	0.238	0.539	.018	24	view →
MESO	DFS	Tertile	III,IV	0.637	0.325	.019	21	view →
KIRP	DFS	Tertile	II,III,IV	0.444	0.786	.024	18	view →
UCS	DFS	Tertile	IV	0.996	0.570	.039	18	view →
READ	DFS	Tertile	IV	0.295	0.661	.021	18	view →
DLBC	OS	Tertile	All	0.136	0.812	.004	15	view →
COAD	OS	Tertile	III,IV	0.875	0.647	.013	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

RNU6-1143P–UVM (OS)

Open the UVM breakdown →