RNU6-1141P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1141P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU6-1141P data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher RNU6-1141P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1141P expression acts as an unfavorable survival marker, although some lineages such as PAAD show a favorable association.

READ, SKCM, and CESC are the cancer types where RNU6-1141P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
READDFSTertileAll0.2470.823<.00181view →
SKCMDFSTertileIV0.0360.433<.00142view →
CESCOSTertileAll0.6650.884.00236view →
PCPGOSTertileAll0.8881.000.00230view →
LIHCOSTertileII,III,IV0.0930.696<.00127view →
LUADDFSTertileIV0.0470.565<.00118view →
COADOSTertileIII,IV0.2150.699.01218view →
OVOSMedianAll0.8100.867.01514view →
BLCADFSTertileIV0.3080.496.0299view →
CHOLOSTertileAll0.1540.793.0049view →
THYMDFSTertileIII,IV0.2050.774.0079view →
PAADOSTertileAll1.0000.560.0443view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

Exploration