RNU6-1136P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1136P RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated RNU6-1136P data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RNU6-1136P RNA is associated with better overall survival. In most high-consensus cancer types, elevated RNU6-1136P expression acts as an unfavorable survival marker, although some lineages such as BRCA and BLCA show a favorable association.

BRCA, KIRC, and BLCA are the cancer types where RNU6-1136P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCAOSTertileAll0.9520.891<.00195view →
KIRCDFSMedianAll0.5330.697.00183view →
BLCAOSTertileII,III,IV0.8180.683.00366view →
KIRPOSMedianIII,IV0.8030.495.00356view →
COADDFSMedianAll0.5950.775<.00145view →
ACCDFSQuartileII,III,IV0.3610.659.01518view →
UVMDFSMedianIII,IV0.2600.685.00617view →
HNSCOSMedianII,III,IV0.7230.618.01516view →
PRADDFSMedianAll0.8390.927.00114view →
PAADOSTertileAll0.6800.252.00913view →
DLBCDFSMedianIV1.0000.412.00611view →
KICHDFSMedianII,III,IV0.7040.960.0108view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

RNU6-1136P–BRCA (OS)

Kaplan–Meier survival curve for RNU6-1136P RNA-high vs -low samples in BRCA.

Open the BRCA breakdown →

Exploration