RNU6-1128P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1128P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU6-1128P data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher RNU6-1128P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1128P expression acts as an unfavorable survival marker, although some lineages such as ESCA and LUAD show a favorable association.

CHOL, ACC, and KIRP are the cancer types where RNU6-1128P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CHOLOSTertileAll0.1850.798<.001108view →
ACCDFSTertileAll0.0100.624<.00184view →
KIRPOSTertileII,III,IV0.2150.769<.00172view →
KIRCDFSQuartileAll0.4810.663.00656view →
TGCTOSTertileII,III,IV0.6701.000.00530view →
LGGDFSTertileAll0.7360.843.01821view →
ESCADFSMedianII,III,IV0.4080.209.00515view →
READDFSTertileII,III,IV0.3230.560.04015view →
LUADOSTertileIII,IV0.8330.619.02212view →
OVOSTertileII,III,IV0.8940.824.0238view →
LAMLDFSMedianAll0.2760.529.0378view →
BLCADFSTertileIV0.7070.380.0443view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

Exploration