RNU6-1126P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1126P RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated RNU6-1126P data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher RNU6-1126P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNU6-1126P expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

ESCA, ACC, and LGG are the cancer types where RNU6-1126P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ESCADFSTertileIII,IV0.8530.249.002105view →
ACCOSTertileAll0.1130.822<.00163view →
LGGOSTertileAll0.4740.816<.00151view →
UCECDFSTertileII,III,IV0.5440.826.01336view →
KIRCDFSTertileII,III,IV0.1000.761<.00118view →
STADDFSTertileIV0.0830.379.0019view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration