RNU6-1119P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1119P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU6-1119P data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher RNU6-1119P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1119P expression acts as an unfavorable survival marker, although some lineages such as BRCA show a favorable association.

SKCM, PAAD, and COAD are the cancer types where RNU6-1119P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SKCMDFSTertileAll0.2470.647<.00136view →
PAADDFSTertileAll0.0930.473<.00136view →
COADDFSTertileIII,IV0.0350.698<.00136view →
HNSCDFSTertileIV0.1000.670<.00127view →
LIHCOSTertileIII,IV0.2020.653.00927view →
BRCAOSTertileII,III,IV0.8360.533.01424view →
UVMDFSTertileAll0.1800.744.01918view →
PCPGDFSTertileAll0.6890.944<.00115view →
PRADOSTertileAll0.9040.996<.00112view →
STADOSTertileIII,IV0.1610.506.0459view →
Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

Exploration