RNU6-1116P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1116P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RNU6-1116P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-1116P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1116P expression acts as an unfavorable survival marker.

KIRC, PAAD, and BRCA are the cancer types where RNU6-1116P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSTertileIII,IV0.3570.659<.00190view →
PAADOSTertileAll0.1000.590<.00172view →
BRCAOSTertileIII,IV0.2070.833<.00166view →
TGCTDFSTertileII,III,IV0.0150.919<.00154view →
STADOSTertileIV0.0630.510<.00145view →
ACCDFSTertileAll0.0660.667.00236view →
UCECOSTertileIV0.3080.748.00936view →
THYMDFSTertileAll0.1740.759.02827view →
SKCMOSTertileIII,IV0.2960.707.01924view →
GBMDFSTertileAll0.0710.288.00918view →
LIHCOSTertileAll0.0250.775<.00118view →
Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

RNU6-1116P–KIRC (DFS)

Kaplan–Meier survival curve for RNU6-1116P RNA-high vs -low samples in KIRC.

Open the KIRC breakdown →

Exploration