RNU6-1114P

Across TCGA pan-cancer cohorts, RNU6-1114P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-1114P data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher RNU6-1114P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1114P expression acts as an unfavorable survival marker, although some lineages such as STAD and OV show a favorable association.

CESC, KICH, and KIRC are the cancer types where RNU6-1114P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Tertile	III,IV	0.227	0.768	<.001	102	view →
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
KIRC	OS	Tertile	All	0.459	0.659	.001	72	view →
SKCM	OS	Tertile	All	0.778	0.888	<.001	69	view →
PAAD	OS	Tertile	All	0.392	0.610	.007	45	view →
PCPG	OS	Tertile	All	0.078	0.955	<.001	36	view →
LIHC	DFS	Tertile	II,III,IV	0.094	0.470	.001	27	view →
ACC	DFS	Tertile	II,III,IV	0.242	0.724	.034	18	view →
ESCA	DFS	Quartile	All	0.378	0.569	.004	13	view →
STAD	OS	Tertile	IV	0.682	0.258	.040	9	view →
OV	OS	Tertile	III,IV	0.405	0.303	.049	6	view →
COAD	DFS	Tertile	All	0.908	0.761	.047	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

RNU6-1114P–CESC (DFS)

Open the CESC breakdown →