RNU6-1110P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1110P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RNU6-1110P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-1110P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1110P expression acts as an unfavorable survival marker, although some lineages such as LUSC and UCS show a favorable association.

KIRC, DLBC, and SKCM are the cancer types where RNU6-1110P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSTertileIV0.0640.642<.001105view →
DLBCOSTertileII,III,IV0.1720.949<.00172view →
SKCMOSTertileAll0.7520.894.00154view →
LUSCDFSTertileAll0.8560.721.00254view →
COADOSTertileIV0.0390.660<.00145view →
PAADOSTertileAll0.2260.599<.00136view →
READOSTertileII,III,IV0.5270.933<.00136view →
KIRPDFSTertileAll0.4650.870.00115view →
UCSDFSTertileIII,IV1.0000.222.04612view →
LGGOSMedianAll0.9250.865.01011view →
LIHCDFSTertileAll0.0980.530.0059view →
Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

RNU6-1110P–KIRC (DFS)

Kaplan–Meier survival curve for RNU6-1110P RNA-high vs -low samples in KIRC.

Open the KIRC breakdown →

Exploration