Across TCGA pan-cancer cohorts, RNU6-1109P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU6-1109P’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RNU6-1109P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-1109P is over-expressed in tumor, although a few such as BRCA and LUAD show the opposite, repressed pattern.

BRCA, KIRC, and LUAD are the cancer types where RNU6-1109P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-1109P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	All	−0.062	.002	4	view →
KIRC	All	III,IV	+0.103	.016	2	view →
LUAD	Female	All	−0.113	.048	1	view →
STAD	All	All	+0.110	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNU6-1109P RNA expression & survival · all RNU6-1109P data types