RNU6-1105P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1105P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-1105P data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher RNU6-1105P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1105P expression acts as an unfavorable survival marker, although some lineages such as UCS show a favorable association.

ESCA, SKCM, and BLCA are the cancer types where RNU6-1105P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ESCAOSTertileIV0.1270.571.00381view →
SKCMDFSTertileII,III,IV0.4630.733.00260view →
BLCADFSTertileAll0.1020.344.01160view →
UCSDFSTertileII,III,IV0.8800.362.01436view →
UCECOSTertileIII,IV0.1100.830<.00136view →
LUADOSTertileII,III,IV0.2160.749.00827view →
COADOSTertileIII,IV0.4060.798.01421view →
PAADDFSTertileAll0.2850.495.03418view →
OVDFSTertileIV0.2540.489.03718view →
KIRCDFSTertileAll0.1800.630.02912view →
GBMDFSTertileAll0.1020.303.0049view →
STADDFSQuartileAll0.3370.529.0386view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

Exploration