RNU6-1101P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1101P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNU6-1101P data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher RNU6-1101P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1101P expression acts as an unfavorable survival marker, although some lineages such as HNSC and BLCA show a favorable association.

CHOL, COAD, and KICH are the cancer types where RNU6-1101P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CHOLOSTertileII,III,IV0.0890.712.00190view →
COADOSTertileAll0.1390.802<.00190view →
KICHDFSTertileAll0.0790.891<.00184view →
LIHCOSTertileII,III,IV0.0590.772<.00145view →
KIRCOSTertileAll0.4720.670.00230view →
ESCAOSTertileII,III,IV0.1050.867.01618view →
LGGOSTertileAll0.6340.892.00518view →
CESCDFSTertileII,III,IV0.1730.705.02818view →
HNSCOSTertileII,III,IV0.8920.655.02415view →
BLCAOSTertileIII,IV0.8370.528.0319view →
SARCDFSTertileAll0.1300.632.0459view →
PAADOSTertileAll0.2160.639.0469view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

RNU6-1101P–CHOL (OS)

Kaplan–Meier survival curve for RNU6-1101P RNA-high vs -low samples in CHOL.

Open the CHOL breakdown →

Exploration